Spider bite or skin infection?

Most wounds diagnosed as spider bites are bacterial skin infections. Unless a spider was seen biting, treat a hot, spreading, painful lesion as a possible infection — that assumption is right far more often and it changes the treatment.

Side by side

Wolf spider biteBrown recluse spider bite
Looks likea red swollen area with two faint puncture pointsa red bump that may develop a pale or blue-grey centre and, in a minority of cases, an ulcer
Patternsingle sitesingle site
Size5–30 mm5–50 mm
Appearsimmediate sharp painoften painless at first
Lastsusually resolves in a few daysmost heal in weeks; a true necrotic lesion can take months
Itch●●○○○ 2/5●●○○○ 2/5
Pain●●●○○ 3/5●●●●○ 4/5
Usually onhands, feet, lower legstorso under clothing, upper arms, thighs — often where clothing was put on with the spider inside
Activenight — this spider hunts on the ground rather than building a webnight
Where fromlawns, gardens, garages and basements across the whole countryundisturbed storage — boxes, wardrobes, behind furniture — in the south-central states
Disease risknone known in the USnone known in the US

What actually settles it

Did anyone see a spider? If not, the odds strongly favour infection. Spiders bite defensively, when pressed against skin — usually while dressing, gardening or moving stored boxes.

Direction of travel. Infection expands and worsens over days, with heat and increasing pain. A genuine bite reaction is worst early and then settles.

Fever points to infection.

Multiple lesions are almost never spider bites — spiders bite once.

Why it matters: infection needs antibiotics. Wound care aimed at a suspected recluse bite while a staph infection spreads is a bad trade. If it is hot, spreading and painful, be seen.

When either one needs a doctor

Questions

Can you have both at once?

Yes, and it happens more often than people expect — which is why the pattern of the bites matters more than any single mark.

Which one is more serious?

Neither carries a significant disease risk in the US. For both, the common complication is infection from scratching.

What if I still cannot tell?

Photograph the bites over several days and note where on your body they appear and when. Progression and position identify a bite far more reliably than a single photograph.

Get a photo assessment in the app

Everything above is free to read. The app adds what a page cannot: point your camera at the bite and get an assessment of the most likely cause, a severity read, and a day-by-day care plan — including the specific signs that mean you should be seen.

Download for iPhone — free

iPhone and iPad. Free to download.